I love the comfort of these shoes, they are almost like an extreme approach shoe. I can wear them all day while climbing, belaying and scrambling or rocks.
I sized them one size smaller than my street shoe for added comfort.

Super super comfortable shoe. I can climb hard all day in these and never feel it. Well, actully I usually feel pain as soon as I start climbing but that's because there are big holes in the toes. I refuse to get rid of them!
Great shoes.

FIT: I sized them 2 sizes below my street shoe (UK 12). The Ascents felt too comfortable the first time I put them on...where was the painful toe curling like a talon? After wearing them for a 5 hour indoor stint, I couldn't believe how well they performed with and with such comfort.
SOLE: Well what can I say about C4 that hasn't already been said. I thought it was a little dramatised, but while bouldering and trad climbing outdoor this shoe has done everything necessary. Even the much debated padded heel was fine for heel hooking.
LOOK: A lot of people have said that they look ridiculous and it's their only drawback...well I think they look fine. Much like Tom Cruise's shoe in MI:2.
USE: I agree that they're an "everything" shoe and I bought them for that purpose, but outdoor is where they shine for me. Bouldering or trad climbing, I've got complete faith in these shoes.
OVERALL: You can buy them cheap if you shop online, but make sure you size them up. The perfect comparison is anything Five Ten, but for me the fit matched the Spires. Will be sticking with Five Ten from now on.

Excellent all-day shoes. The heel padding makes heel-hooks damned-near impossible, but at the same time makes walk-offs or hard landings much easier. Very comfortable toe box, easy-on/easy-off velcro make them a great choice for your multipitch trad shoes. I use a pair of T-Rocks when I want to edge on a dime.

I just can't get enough Five Ten. Living close to their outlet store in Redlands, CA is something I strive to take advantage of. This new(?) shoe is perfect for where I liove and climb the most, the canyons of Red Rock, Nevada. Slip lasted for flexibilty and sensitivity while smearing on varnsihed face holds, with a generous footbox that gives good purchase in small cracks as well. The padded double tongues with velcro closures make it great to ease the comfort on long belays. I'm not a big fan of the padded heel as far as technical climbing applications, but it does add some cushion on walk-offs, at the expense of making hard heel hooking a little difficult to pull-off. Like all general/all purpose shoes this one has some cons, one of them being it's edging abilty. But if one is not pushing the limits on 5.12 dime edges, it should not be an issue. C4 Rubber is still the best and a good price point and I give this shoe an overall grade of A-.